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    6/25/2010 - The P53 Family: New Book Reviews Research On The 'Guardian Of The Genome'
    Posted in Medical News

    The p53 tumor suppressor gene, the "guardian of the genome," protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of proteins that set cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby llc. to tumor malignancy. A new book from Cold Spring Harbor Laboratory Press, The p53 Family, provides a widespread


    copyrights:cite this source synonym collection v1.1copyright © 2008 by lexico publishing group review of the functions of the p53 family. It was edited by Arnold Levine and David Lane, who independently discovered p53 about 30 years ago...



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