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    8/3/2012 - Mechanism Of Lung Cancer-Associated Mutations Suggests New Therapeutic Approaches
    Posted in Medical News

    Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most normally mutated in lung cancer may promote such tumors. The panel found that the protein encoded by this gene, called EPHA3, commonly inhibits tumor formation, and that loss or mutation of the gene - as often happens in lung cancer - denature this tumor-suppressive effect, potentially sparking the formation of lung cancer. The findings, published July 24 in the Journal of the national Cancer Institute, could offer control for personalizing cancer treatments and progress of new therapies...

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